{"id":2130,"date":"2023-04-20T06:03:25","date_gmt":"2023-04-20T10:03:25","guid":{"rendered":"https:\/\/parmaks.com\/Resources\/dr-gul-dolen-on-rethinking-psychedelics-new-applications-autism-stroke-and-allergies-the-neurobiology-of-beginners-mind-octopuses-on-mdma-and-the-master-key-of-metaplasticity-667\/"},"modified":"2023-04-20T06:03:25","modified_gmt":"2023-04-20T10:03:25","slug":"dr-gul-dolen-on-rethinking-psychedelics-new-applications-autism-stroke-and-allergies-the-neurobiology-of-beginners-mind-octopuses-on-mdma-and-the-master-key-of-metaplasticity-667","status":"publish","type":"post","link":"https:\/\/parmaks.com\/Resources\/dr-gul-dolen-on-rethinking-psychedelics-new-applications-autism-stroke-and-allergies-the-neurobiology-of-beginners-mind-octopuses-on-mdma-and-the-master-key-of-metaplasticity-667\/","title":{"rendered":"Dr. G\u00fcl D\u00f6len on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner\u2019s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity (#667)"},"content":{"rendered":"<p> <a href=\"https:\/\/hop.clickbank.net\/?affiliate=infohatch&amp;vendor=J1R2C\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-10614 aligncenter\" src=\"http:\/\/parmaks.com\/Resources\/wp-content\/uploads\/2025\/05\/profit-gen400px.png\" alt=\"Profit Gen\" width=\"400\" height=\"217\" srcset=\"https:\/\/parmaks.com\/Resources\/wp-content\/uploads\/2025\/05\/profit-gen400px.png 400w, https:\/\/parmaks.com\/Resources\/wp-content\/uploads\/2025\/05\/profit-gen400px-300x163.png 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/a><br \/>\n<\/p>\n<div>\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"480\" alt=\"\" class=\"wp-image-67133 jetpack-lazy-image\" data-recalc-dims=\"1\" srcset=\"https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=1024%2C819&amp;ssl=1 1024w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=300%2C240&amp;ssl=1 300w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=768%2C614&amp;ssl=1 768w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=1536%2C1229&amp;ssl=1 1536w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=2048%2C1638&amp;ssl=1 2048w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?w=1800&amp;ssl=1 1800w\" data-lazy-sizes=\"(max-width: 767px) 90vw, 600px\" src=\"https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration.jpeg?resize=600%2C480&amp;is-pending-load=1#038;ssl=1\"\/><noscript><img loading=\"lazy\" data-lazy-fallback=\"1\" decoding=\"async\" width=\"600\" height=\"480\" src=\"https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration.jpeg?resize=600%2C480&amp;ssl=1\" alt=\"\" class=\"wp-image-67133\" srcset=\"https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=1024%2C819&amp;ssl=1 1024w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=300%2C240&amp;ssl=1 300w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=768%2C614&amp;ssl=1 768w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=1536%2C1229&amp;ssl=1 1536w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?resize=2048%2C1638&amp;ssl=1 2048w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/tim.blog\/wp-content\/uploads\/2023\/04\/Gul-Dolen-Illustration-scaled.jpeg?w=1800&amp;ssl=1 1800w\" sizes=\"auto, (max-width: 767px) 90vw, 600px\" data-recalc-dims=\"1\"\/><\/noscript><figcaption class=\"wp-element-caption\">Illustration via <a href=\"http:\/\/99designs.com\/tim\" data-wpel-link=\"external\" rel=\"nofollow external noopener noreferrer\">99designs<\/a><\/figcaption><\/figure>\n<blockquote class=\"wp-block-quote\">\n<p><strong><strong>\u201cPsychedelics have this property, which William James pointed out over 100 years ago, of creating this sense of what he called the noetic property, this feeling that \u2018Now that I\u2019ve had this experience, I know the really real. The true truth has been revealed to me, and everything before this moment was just a facade or some lesser truth or some limited access to the truth. But now I really know.\u2019 For a scientist, that\u2019s pretty dangerous.\u201d<\/strong><\/strong><\/p>\n<p><cite>\u2014 Dr. G\u00fcl D\u00f6len<\/cite><\/p><\/blockquote>\n<p><strong>Dr. G\u00fcl D\u00f6len<\/strong>\u00a0is an associate professor of neuroscience at the Johns Hopkins University School of Medicine and a pioneer and world leader of psychedelics research. Her\u00a0<a href=\"http:\/\/www.dolenlab.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">laboratory<\/a>\u00a0has discovered a novel mechanism that could account for the broad range of therapeutic applications that psychedelics are currently being tested for. Her lab has discovered a novel critical period for social reward learning and shown that this critical period can be reopened with psychedelic drugs, such as MDMA, LSD, psilocybin, ketamine, and ibogaine. Building on this discovery, she has formulated the hypothesis that psychedelics may be the long sought \u201cmaster key\u201d for unlocking critical periods across the brain. To test this hypothesis, she has initiated a nationwide, collaborative effort to determine whether psychedelics reopen critical periods for ocular dominance plasticity, bird song learning, anatomical plasticity in the barrel cortex, serotonergic neuronal regeneration, dendritic spinogenesis, and motor learning.<\/p>\n<p>Importantly, understanding psychedelics through this framework dramatically expands the scope of disorders (including autism, stroke, and allergies) that might benefit from adjunct therapy with psychedelics, an approach she has dubbed\u00a0<a href=\"http:\/\/www.phathomproject.org\/\" rel=\"noreferrer noopener nofollow external\" target=\"_blank\" data-wpel-link=\"external\">the\u00a0<strong>PHATHOM<\/strong>\u00a0project<\/a>\u00a0(Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability).\u00a0<\/p>\n<p>Dr. D\u00f6len earned her MD, PhD at Brown University and the Massachusetts Institute of Technology (MIT), where she carried out seminal work on critical periods, learning and memory, and the pathogenesis of autism.\u00a0<\/p>\n<p>Please enjoy!<\/p>\n<p class=\"wp-embed-aspect-16-9 wp-has-aspect-ratio\"><strong><em><strong><em>Listen to the episode on <a href=\"https:\/\/podcasts.apple.com\/us\/podcast\/667-dr-g%C3%BCl-d%C3%B6len-on-rethinking-psychedelics-new-applications\/id863897795?i=1000609648789\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Apple Podcasts<\/a>, <a href=\"https:\/\/open.spotify.com\/episode\/222G25SC3xBinKIKp61fY0\" data-wpel-link=\"external\" rel=\"nofollow external noopener noreferrer\">Spotify<\/a>, <a href=\"https:\/\/overcast.fm\/+KebuBi-_0\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Overcast<\/a>, <a href=\"https:\/\/podcastaddict.com\/podcast\/2031148#\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Podcast Addict<\/a>, <a href=\"https:\/\/pca.st\/timferriss\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Pocket Casts<\/a>, <a href=\"https:\/\/castbox.fm\/channel\/id1059468?country=us\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Castbox<\/a>, <a href=\"https:\/\/podcasts.google.com\/?feed=aHR0cHM6Ly9yc3MuYXJ0MTkuY29tL3RpbS1mZXJyaXNzLXNob3c&amp;ved=0CAAQ4aUDahcKEwjI_ezXzuDnAhUAAAAAHQAAAAAQAQ\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Google Podcasts<\/a>, <a href=\"https:\/\/www.stitcher.com\/show\/the-tim-ferriss-show\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Stitcher<\/a>, <strong><em><strong><em><a href=\"https:\/\/music.amazon.com\/podcasts\/9814f3cc-1dc5-4003-b816-44a8eb6bf666\/the-tim-ferriss-show\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Amazon Music<\/a>,\u00a0<\/em><\/strong><\/em><\/strong>or on your favorite podcast platform<\/em><\/strong><\/em><\/strong><em><strong>.<\/strong><\/em> <strong><em><a href=\"https:\/\/youtu.be\/Pt9_E4ZR5S0\" data-wpel-link=\"external\" rel=\"nofollow external noopener noreferrer\">Watch the interview on YouTube here<\/a>.<\/em><\/strong><\/p>\n<p class=\"wp-embed-aspect-16-9 wp-has-aspect-ratio\"><strong><em><strong><em><strong><em><strong><em><strong><em><strong><em><strong><em><strong><em><strong><em><strong><em>Brought to you by\u00a0<\/em><\/strong><a href=\"http:\/\/drinklmnt.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong><em>LMNT<\/em><\/strong><\/a><strong><em>\u00a0electrolyte supplement,\u00a0<\/em><\/strong><a href=\"http:\/\/helixsleep.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong><em>Helix Sleep<\/em><\/strong><\/a><strong><em>\u00a0premium mattresses, and\u00a0<\/em><\/strong><a href=\"http:\/\/athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong><em>Athletic Greens\u2019s AG1<\/em><\/strong><\/a><strong><em>\u00a0all-in-one nutritional supplement.<\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/em><\/strong><\/p>\n<div class=\"wp-block-tim-podcast-link-main podcast-block wp-embed-aspect-16-9 wp-has-aspect-ratio\"><a class=\"podcast-block__link\" target=\"_blank\" rel=\"noopener noreferrer nofollow external\" href=\"https:\/\/podcasts.apple.com\/us\/podcast\/667-dr-g%C3%BCl-d%C3%B6len-on-rethinking-psychedelics-new-applications\/id863897795?i=1000609648789\" data-wpel-link=\"external\"><img decoding=\"async\" class=\"podcast-block__link-icon jetpack-lazy-image\" data-recalc-dims=\"1\" src=\"https:\/\/i0.wp.com\/tim.blog\/wp-content\/themes\/timferriss\/inc\/blocks\/podcast-link\/images\/apple-podcast.png?w=600&amp;is-pending-load=1#038;ssl=1\" srcset=\"https:\/\/tim.blog\/data:image\/gif;base64,https:\/\/tim.blog\/R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\"\/><noscript><img data-lazy-fallback=\"1\" decoding=\"async\" src=\"https:\/\/i0.wp.com\/tim.blog\/wp-content\/themes\/timferriss\/inc\/blocks\/podcast-link\/images\/apple-podcast.png?w=600&amp;ssl=1\" class=\"podcast-block__link-icon\" data-recalc-dims=\"1\"\/><\/noscript><span class=\"podcast-block__link-text-top\">Listen on<\/span><span class=\"podcast-block__link-text\">Apple Podcasts<\/span><\/a><\/div>\n<div class=\"wp-block-tim-podcast-link-main podcast-block wp-embed-aspect-16-9 wp-has-aspect-ratio\"><a class=\"podcast-block__link\" target=\"_blank\" rel=\"noopener noreferrer nofollow external\" href=\"https:\/\/open.spotify.com\/episode\/222G25SC3xBinKIKp61fY0\" data-wpel-link=\"external\"><img decoding=\"async\" class=\"podcast-block__link-icon jetpack-lazy-image\" src=\"https:\/\/tim.blog\/wp-content\/themes\/timferriss\/inc\/blocks\/podcast-link\/images\/spotify.svg?is-pending-load=1\" srcset=\"https:\/\/tim.blog\/data:image\/gif;base64,https:\/\/tim.blog\/R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\"\/><noscript><img data-lazy-fallback=\"1\" decoding=\"async\" src=\"https:\/\/tim.blog\/wp-content\/themes\/timferriss\/inc\/blocks\/podcast-link\/images\/spotify.svg\" class=\"podcast-block__link-icon\"\/><\/noscript><span class=\"podcast-block__link-text-top\">Listen on<\/span><span class=\"podcast-block__link-text\">Spotify<\/span><\/a><\/div>\n<div class=\"wp-block-tim-podcast-link-main podcast-block wp-embed-aspect-16-9 wp-has-aspect-ratio\"><a class=\"podcast-block__link\" target=\"_blank\" rel=\"noopener noreferrer nofollow external\" href=\"https:\/\/overcast.fm\/+KebuK01Cc\" data-wpel-link=\"external\"><img decoding=\"async\" class=\"podcast-block__link-icon jetpack-lazy-image\" src=\"https:\/\/tim.blog\/wp-content\/themes\/timferriss\/inc\/blocks\/podcast-link\/images\/overcast.svg?is-pending-load=1\" srcset=\"https:\/\/tim.blog\/data:image\/gif;base64,https:\/\/tim.blog\/R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\"\/><noscript><img data-lazy-fallback=\"1\" decoding=\"async\" src=\"https:\/\/tim.blog\/wp-content\/themes\/timferriss\/inc\/blocks\/podcast-link\/images\/overcast.svg\" class=\"podcast-block__link-icon\"\/><\/noscript><span class=\"podcast-block__link-text-top\">Listen on<\/span><span class=\"podcast-block__link-text\">Overcast<\/span><\/a><\/div>\n<div class=\"podcast-player\">\n<div class=\"podcast-player-inner-wrap\">\n<p>#667: Dr. G\u00fcl D\u00f6len on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner\u2019s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity<\/p>\n<p><noscript><iframe src=\"https:\/\/www.art19.com\/shows\/58dacbdc-646e-4585-9914-19c3de11d1ba\/episodes\/7f51f097-60c6-4577-99f3-0babe4b194c7\/embed?type=micro\" style=\"width: 100%; height: 30px; border: 0 none;\" scrolling=\"no\"><\/iframe><\/noscript><\/div>\n<\/div>\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\n<p>\n<span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe loading=\"lazy\" title=\"Rethinking Psychedelics, Octopuses on MDMA, and The Master Key of Metaplasticity | Dr. G\u00fcl D\u00f6len\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/Pt9_E4ZR5S0?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/span>\n<\/p>\n<\/figure>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<p><strong>This episode is brought to you by\u00a0<\/strong><a href=\"https:\/\/www.athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong>Athletic Greens<\/strong><\/a><strong>.<\/strong>\u00a0I get asked all the time, \u201cIf you could use only one supplement, what would it be?\u201d My answer is usually\u00a0<a href=\"https:\/\/www.athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">AG1<\/a> by <a href=\"https:\/\/www.athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Athletic\u00a0Greens<\/a>, my all-in-one nutritional insurance. I recommended it in\u00a0<em>The 4-Hour Body<\/em>\u00a0in 2010 and did not get paid to do so. I do my best with nutrient-dense meals, of course, but\u00a0<a href=\"https:\/\/www.athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">AG1<\/a>\u00a0further covers my bases with vitamins, minerals, and whole-food-sourced micronutrients that support gut health and the immune system.\u00a0<\/p>\n<p><strong>Right now,\u00a0<\/strong><a href=\"https:\/\/www.athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong>Athletic Greens<\/strong><\/a><strong>\u00a0is offering you their Vitamin D Liquid Formula free with your first subscription purchase<\/strong>\u2014a vital nutrient for a strong immune system and strong bones.\u00a0<strong>Visit\u00a0<\/strong><a href=\"https:\/\/www.athleticgreens.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong>AthleticGreens.com\/Tim<\/strong><\/a><strong>\u00a0to claim this special offer today and receive the free Vitamin D Liquid Formula (and 5 free travel packs) with your first subscription purchase!\u00a0<\/strong>That\u2019s up to a one-year supply of Vitamin D as added value when you try their delicious and comprehensive all-in-one daily greens product.<\/p>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<p><strong>This episode is brought to you by\u00a0<a href=\"http:\/\/helixsleep.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\"><strong>Helix Sleep<\/strong><\/a>!\u00a0<\/strong>Helix was selected as the best overall mattress of 2022 by\u00a0<em>GQ\u00a0<\/em>magazine<em>, Wired,\u00a0<\/em>and Apartment Therapy. With\u00a0<a href=\"http:\/\/helixsleep.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Helix<\/a>, there\u2019s a specific mattress to meet each and every body\u2019s unique comfort needs. Just take their quiz\u2014<a href=\"http:\/\/helixsleep.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">only two minutes to complete<\/a>\u2014that matches your body type and sleep preferences to the perfect mattress for you. They have a 10-year warranty, and you get to try it out for a hundred nights, risk-free. They\u2019ll even pick it up from you if you don\u2019t love it.\u00a0<strong>And now, Helix is offering 20% off all mattress orders plus two free pillows at\u00a0<a href=\"http:\/\/helixsleep.com\/tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">HelixSleep.com\/Tim<\/a>.<\/strong><\/p>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<p><strong>This episode is brought to you by\u00a0<a rel=\"noreferrer noopener nofollow external\" href=\"http:\/\/drinklmnt.com\/tim\" target=\"_blank\" data-wpel-link=\"external\">LMNT<\/a>!\u00a0<\/strong>What is LMNT? It\u2019s a\u00a0<a rel=\"noreferrer noopener nofollow external\" href=\"http:\/\/drinklmnt.com\/tim\" target=\"_blank\" data-wpel-link=\"external\">delicious, sugar-free electrolyte drink mix<\/a>. I\u2019ve stocked up on boxes and boxes of this and usually use it 1\u20132 times per day.\u00a0<a rel=\"noreferrer noopener nofollow external\" href=\"http:\/\/drinklmnt.com\/tim\" target=\"_blank\" data-wpel-link=\"external\">LMNT<\/a>\u00a0is formulated to help anyone with their electrolyte needs and perfectly suited to folks following a keto, low-carb, or Paleo diet. If you are on a low-carb diet or fasting, electrolytes play a key role in relieving hunger, cramps, headaches, tiredness, and dizziness.<\/p>\n<p><a href=\"http:\/\/DrinkLMNT.com\/Tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">LMNT<\/a>\u00a0came up with a very special offer for you, my dear listeners.\u00a0<strong>For a limited time, you can get a free <a href=\"http:\/\/DrinkLMNT.com\/Tim\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">LMNT<\/a> Sample Pack with any purchase. This special offer is available here: <a rel=\"noreferrer noopener nofollow external\" href=\"http:\/\/DrinkLMNT.com\/Tim\" target=\"_blank\" data-wpel-link=\"external\">DrinkLMNT.com\/Tim<\/a>. <\/strong><\/p>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<p><strong><a href=\"https:\/\/tim.blog\/2022\/09\/02\/dr-suresh-muthukumaraswamy\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-wpel-link=\"internal\">Want to hear<\/a> an episode with someone else who\u2019s pushing us toward a greater understanding of how psychedelics can be used to heal us?<\/strong> Listen to my conversation with <a href=\"https:\/\/tim.blog\/2022\/09\/02\/dr-suresh-muthukumaraswamy\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-wpel-link=\"internal\">Dr. Suresh Muthukumaraswamy<\/a>, in which we discussed how ketamine differs from other psychedelics, obstacles to getting ketamine labeled as an antidepressant, the difficulty of applying placebo controls to psychedelic research, avoiding another 50 years of psychedelic research darkness, where aspiring psychedelic researchers should focus their education, <a href=\"https:\/\/tim.blog\/2022\/09\/02\/dr-suresh-muthukumaraswamy\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-wpel-link=\"internal\">and much more<\/a>.<\/p>\n<div class=\"podcast-player\">\n<div class=\"podcast-player-inner-wrap\">\n<p>#619: Dr. Suresh Muthukumaraswamy \u2014 LSD Microdosing, Classical Psychedelics vs. Ketamine, Science and Speed in New Zealand, Placebo Options, and The Infinite Possibilities of Studying Mind-Altering Compounds<\/p>\n<p><noscript><iframe src=\"https:\/\/www.art19.com\/shows\/58dacbdc-646e-4585-9914-19c3de11d1ba\/episodes\/e823c8d4-fd6a-4e1a-9ae5-5e45eb1155fe\/embed?type=micro\" style=\"width: 100%; height: 30px; border: 0 none;\" scrolling=\"no\"><\/iframe><\/noscript><\/div>\n<\/div>\n<p><strong>What was your favorite quote or lesson from this episode? Please let me know <a href=\"https:\/\/tim.blog\/2023\/04\/19\/gul-dolen\/#respond\">in the comments<\/a>.<\/strong><\/p>\n<p><strong>SCROLL BELOW FOR LINKS AND SHOW NOTES\u2026<\/strong><\/p>\n<p><span id=\"more-67131\"\/><\/p>\n<h3 class=\"wp-block-heading\">SELECTED LINKS FROM THE EPISODE<\/h3>\n<ul>\n<li><a href=\"http:\/\/www.dolenlab.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">d\u00f6lenLAB<\/a><\/li>\n<li><a href=\"http:\/\/www.dolenlab.org\/phathom-project\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">PHATHOM project<\/a><\/li>\n<li><a href=\"https:\/\/www.hopkinsmedicine.org\/research\/advancements-in-research\/fundamentals\/profiles\/gul-dolen\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Gul Dolen on Philosophy, Neuroscience, and the Study of Autism | Hopkins Medicine<\/a><\/li>\n<li><a href=\"https:\/\/www.thoughtco.com\/theory-of-mind-4165566\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">What Is Theory of Mind in Psychology? | ThoughtCo.<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/Philosophy_of_mind\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Philosophy of Mind | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/www.spectrumnews.org\/features\/deep-dive\/theory-of-mind-in-autism-a-research-field-reborn\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">\u2018Theory of Mind\u2019 in Autism: A Research Field Reborn | Spectrum Autism Research News<\/a><\/li>\n<li><a href=\"https:\/\/bigthink.com\/neuropsych\/psychopaths-can-empathize-but-the-process-isnt-automatic\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Psychopaths Can Empathize, but the Process Isn\u2019t Automatic | Big Think<\/a><\/li>\n<li><a href=\"https:\/\/news.berkeley.edu\/2015\/08\/12\/octopus-shows-unique-hunting-social-and-sexual-behavior\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Octopus Shows Unique Hunting, Social, and Sexual Behavior | Berkeley News<\/a><\/li>\n<li><a href=\"https:\/\/fragilex.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">What Is Fragile X Syndrome? | The National Fragile X Foundation<\/a><\/li>\n<li><a href=\"https:\/\/dnalc.cshl.edu\/view\/2366-Biochemical-Breakthrough-Fragile-X-Syndrome.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Biochemical Breakthrough: Fragile X Syndrome | CSHL DNA Learning Center<\/a><\/li>\n<li><a href=\"https:\/\/my.clevelandclinic.org\/health\/articles\/24291-diagnostic-and-statistical-manual-dsm-5\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">DSM-5: What It Is and What It Diagnoses | Cleveland Clinic<\/a><\/li>\n<li><a href=\"https:\/\/www.hopkinsmedicine.org\/health\/conditions-and-diseases\/motor-stereotypies\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Motor Stereotypies | Johns Hopkins Medicine<\/a><\/li>\n<li><a href=\"https:\/\/www.psychiatry.org\/patients-families\/autism\/what-is-autism-spectrum-disorder\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">What Is Autism Spectrum Disorder? | APA<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/FMR1\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">FMR1 | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/www.cdc.gov\/ncbddd\/birthdefects\/downsyndrome.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Facts about Down Syndrome | CDC<\/a><\/li>\n<li><a href=\"https:\/\/www.psychiatry.org\/patients-families\/schizophrenia\/what-is-schizophrenia\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">What is Schizophrenia? | APA<\/a><\/li>\n<li><a href=\"https:\/\/www.simplypsychology.org\/Konrad-Lorenz.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Konrad Lorenz\u2019s Imprinting Theory | Simply Psychology<\/a><\/li>\n<li><a href=\"https:\/\/www.simplypsychology.org\/critical-period.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Critical Period In Brain Development and Childhood Learning | Simply Psychology<\/a><\/li>\n<li><a href=\"https:\/\/themicrodose.substack.com\/p\/5-questions-for-gul-dolen\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">5 Questions for Gul Dolen | The Microdose<\/a><\/li>\n<li><a href=\"https:\/\/carla.umn.edu\/immersion\/documents\/ImmersionResearch_TaraFortune.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">What the Research Says About Immersion | CARLA<\/a><\/li>\n<li><a href=\"https:\/\/www.hopkinsmedicine.org\/news\/newsroom\/news-releases\/psychedelic-drug-mdma-may-reawaken-critical-period-in-brain-to-help-treat-ptsd\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Psychedelic Drug MDMA May Reawaken \u2018Critical Period\u2019 in Brain to Help Treat PTSD | Hopkins Medicine<\/a><\/li>\n<li><a href=\"https:\/\/tim.blog\/2021\/03\/31\/psychedelics-101\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-wpel-link=\"internal\">Psychedelics 101: Books, Documentaries, Podcasts, Science, and More | Tim Ferriss<\/a><\/li>\n<li><a href=\"https:\/\/www.scientificamerican.com\/article\/rolling-under-the-sea-scientists-gave-octopuses-ecstasy-to-study-social-behavior\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Rolling under the Sea: Scientists Gave Octopuses Ecstasy to Study Social Behavior | Scientific American<\/a><\/li>\n<li><a href=\"https:\/\/www.ndcn.ox.ac.uk\/divisions\/fmrib\/what-is-fmri\/introduction-to-fmri\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Introduction to fMRI | Nuffield Department of Clinical Neurosciences<\/a><\/li>\n<li><a href=\"https:\/\/www.moleculardevices.com\/applications\/patch-clamp-electrophysiology\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Patch Clamp Electrophysiology | Molecular Devices<\/a><\/li>\n<li><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnins.2021.710004\/full\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Critical Period Plasticity as a Framework for Psychedelic-Assisted Psychotherapy | Frontiers in Neuroscience<\/a><\/li>\n<li><a href=\"http:\/\/www.scholarpedia.org\/article\/Metaplasticity\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Metaplasticity | Scholarpedia<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/NMDA_receptor\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">NMDA Receptor | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/AMPA_receptor\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">AMPA Receptor | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/www.merckmanuals.com\/professional\/special-subjects\/illicit-drugs-and-intoxicants\/ketamine-and-phencyclidine-pcp\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Ketamine and Phencyclidine (PCP): Special Subjects | Merck Manuals Professional Edition<\/a><\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17024679\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Contribution of NR2A and NR2B NMDA Subunits to Bidirectional Synaptic Plasticity in the Hippocampus in Vivo | Hippocampus<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/Metabotropic_glutamate_receptor\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Metabotropic Glutamate Receptor (mGluR) | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/www.cbsnews.com\/news\/weil-says-lsd-cured-his-allergy-01-03-2001\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Weil Says LSD Cured His Allergy | CBS News<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/Serotonin_antagonist_and_reuptake_inhibitor\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Serotonin Antagonist and Reuptake Inhibitor | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/serotonin-antagonist\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Serotonin Antagonist: An Overview | ScienceDirect Topics<\/a><\/li>\n<li><a href=\"https:\/\/www.mdpi.com\/1422-0067\/24\/8\/7049\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Extracellular Matrix Regulation in Physiology and in Brain Disease | International Journal of Molecular Sciences<\/a><\/li>\n<li><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2022.837671\/full\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies | Frontiers in Pharmacology<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/Salvinorin_A\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Salvinorin A | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/en.wikipedia.org\/wiki\/Arrestin\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Arrestin | Wikipedia<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/topics\/neuroscience\/beta-arrestin\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Beta Arrestin: An Overview | ScienceDirect Topics<\/a><\/li>\n<li><a href=\"https:\/\/www.med.unc.edu\/pharm\/a-scientific-first-how-psychedelics-bind-to-key-brain-cell-receptor\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor | Pharmacology<\/a><\/li>\n<li><a href=\"https:\/\/www.med.unc.edu\/pharm\/this-is-lsd-attached-to-a-brain-cell-serotonin-receptor\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">This Is LSD Attached to a Brain Cell Serotonin Receptor | Pharmacology<\/a><\/li>\n<li><a href=\"https:\/\/www.amazon.com\/Pihkal-Chemical-Story-Alexander-Shulgin\/dp\/0963009605?tag=offsitoftimfe-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">PiHKAL: A Chemical Love Story by Alexander Shulgin and Ann Shulgin | Amazon<\/a><\/li>\n<li><a href=\"https:\/\/www.amazon.com\/Tihkal-Continuation-Alexander-Shulgin\/dp\/0963009699?tag=offsitoftimfe-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">TiHKAL: The Continuation by Alexander Shulgin and Ann Shulgin | Amazon<\/a><\/li>\n<li><a href=\"http:\/\/shodor.org\/succeed-1.0\/programs\/compchem97\/serotonin\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">A Comparison of Serotonin and Lysergic Acid | SHODOR<\/a><\/li>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2661189\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Helicobacter Pylori: A Nobel Pursuit? | Canadian Journal of Gastroenterology<\/a><\/li>\n<li><a href=\"https:\/\/www.themarginalian.org\/2018\/06\/04\/william-james-varieties-consciousness\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">William James on Consciousness and the Four Features of Transcendent Experiences | The Marginalian<\/a><\/li>\n<li><a href=\"https:\/\/www.hopkinsmedicine.org\/neurology_neurosurgery\/centers_clinics\/cerebrovascular\/stroke\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Stroke Center | The Johns Hopkins Hospital<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1474442219304156\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Review: Advances and Challenges in Stroke Rehabilitation | The Lancet Neurology<\/a><\/li>\n<li><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2021.685085\/full\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Psychedelics for Brain Injury: A Mini-Review | Frontiers in Neurology<\/a><\/li>\n<li><a href=\"https:\/\/www.theguardian.com\/society\/2023\/jan\/23\/ibogaine-iboga-drug-addiction-psychedelic-gabon\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">The Psychedelic Ibogaine Can Treat Addiction. The Race Is On to Cash In | The Guardian<\/a><\/li>\n<li><a href=\"https:\/\/volteface.me\/protecting-iboga-and-indigenous-voices\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Protecting Iboga and Indigenous Voices | Volteface<\/a><\/li>\n<li><a href=\"https:\/\/tim.blog\/2022\/07\/01\/mark-plotkin-and-hamilton-morris\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-wpel-link=\"internal\">Hamilton Morris and Dr. Mark Plotkin \u2014 Exploring the History of Psychoactive Substances, Synthetic vs. Natural Options, Microdosing, 5-MeO-DMT, The \u201cDrunken Monkey\u201d Hypothesis, Timothy Leary\u2019s Legacy, and More | The Tim Ferriss Show #605<\/a><\/li>\n<li><a href=\"https:\/\/tim.blog\/2020\/09\/30\/mark-plotkin\/\" target=\"_blank\" rel=\"noreferrer noopener\" data-wpel-link=\"internal\">Dr. Mark Plotkin on Ethnobotany, Real vs. Fake Shamans, Hallucinogens, and the Dalai Lamas of South America | The Tim Ferriss Show #469<\/a><\/li>\n<li><a href=\"https:\/\/maps.org\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Multidisciplinary Association for Psychedelic Studies (MAPS)<\/a><\/li>\n<li><a href=\"https:\/\/www.newyorker.com\/magazine\/2015\/11\/23\/helping-hand-annals-of-medicine-karen-russell\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Can Video Games Help Stroke Victims? | The New Yorker<\/a><\/li>\n<li><a href=\"https:\/\/www.spectrumnews.org\/news\/profiles\/in-deep-water-with-gul-dolen\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">In Deep Water with G\u00fcl D\u00f6len | Spectrum Autism Research News<\/a><\/li>\n<li><a href=\"https:\/\/www.nih.gov\/grants-funding\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Grants &amp; Funding | National Institutes of Health (NIH)<\/a><\/li>\n<li><a href=\"https:\/\/www.enttoday.org\/article\/how-to-land-an-nih-grant\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">How to Land an NIH Grant | ENTtoday<\/a><\/li>\n<li><a href=\"https:\/\/www.usatoday.com\/story\/news\/nation\/2021\/02\/21\/covid-pcr-tests-made-possible-yellowstone-finding-thermus-aquaticus\/4533258001\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">How a 1960s Discovery in Yellowstone Made Millions of COVID-19 PCR Tests Possible | USA Today<\/a><\/li>\n<li><a href=\"https:\/\/www.nytimes.com\/2015\/10\/17\/business\/putting-numbers-to-a-tax-increase-for-the-rich.html\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">What Could Raising Taxes on the 1% Do? Surprising Amounts | The New York Times<\/a><\/li>\n<li><a href=\"https:\/\/www.theatlantic.com\/ideas\/archive\/2019\/01\/higher-taxes-rich-wont-suffocate-innovation\/580642\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Higher Taxes on the Rich Won\u2019t Suffocate Innovation | The Atlantic<\/a><\/li>\n<li><a href=\"https:\/\/siepr.stanford.edu\/news\/how-set-top-tax-rates-without-deterring-innovation\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">How to Set Top Tax Rates without Deterring Innovation | Stanford Institute for Economic Policy Research<\/a><\/li>\n<li><a href=\"https:\/\/www.darpa.mil\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Defense Advanced Research Projects Agency (DARPA)<\/a><\/li>\n<li><a href=\"https:\/\/www.amazon.com\/Invisible-Women-Exposing-World-Designed\/dp\/1784706280\/?tag=offsitoftimfe-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Invisible Women: Data Bias in a World Designed for Men by Caroline Criado Perez | Amazon<\/a><\/li>\n<li><a href=\"https:\/\/www.amazon.com\/Dawn-Everything-New-History-Humanity\/dp\/1250858801\/?tag=offsitoftimfe-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">The Dawn of Everything: A New History of Humanity by David Graeber | Amazon<\/a><\/li>\n<li><a href=\"https:\/\/www.amazon.com\/Bullshit-Jobs-Theory-David-Graeber\/dp\/1501143336\/?tag=offsitoftimfe-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Bullshit Jobs: A Theory by David Graeber | Amazon<\/a><\/li>\n<li><a href=\"https:\/\/www.amazon.com\/Immortality-Key-Uncovering-History-Religion\/dp\/1250207142\/?tag=offsitoftimfe-20\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">The Immortality Key: The Secret History of the Religion with No Name by Brian Muraresku | Amazon<\/a><\/li>\n<li><a href=\"https:\/\/www.dogfish.com\/brewery\/beer\/midas-touch\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Midas Touch | Dogfish Head Craft Brewed Ales<\/a><\/li>\n<li><a href=\"https:\/\/whc.unesco.org\/en\/list\/1018\/\" target=\"_blank\" rel=\"noreferrer noopener nofollow external\" data-wpel-link=\"external\">Ephesus | UNESCO World Heritage Centre<\/a><\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">SHOW NOTES<\/h3>\n<ul>\n<li>[06:25] How G\u00fcl designed her own major as an undergrad.<\/li>\n<li>[09:03] Philosophy of mind and theory of mind.<\/li>\n<li>[13:33] What theory of mind in non-human species suggests.<\/li>\n<li>[16:45] The origin of G\u00fcl\u2019s interest in autism.<\/li>\n<li>[21:37] Autism facts vs. fiction.<\/li>\n<li>[28:31] Critical periods.<\/li>\n<li>[37:59] How critical periods apply to therapies for autism.<\/li>\n<li>[43:37]\u00a0<em>Why<\/em>\u00a0might psychedelics allow us to reopen shut critical periods?<\/li>\n<li>[49:25] MDMA and the octopus.<\/li>\n<li>[52:40] Challenging popular notions about psychedelic research.<\/li>\n<li>[54:52] Plasticity.<\/li>\n<li>[1:00:26] Favorite neurotransmitter receptors.<\/li>\n<li>[1:06:03] Can psychedelics cure allergies?<\/li>\n<li>[1:14:00] Seeking a common pathway for the therapeutic effects of psychedelics.<\/li>\n<li>[1:15:54] Potential applications for kappa-opioid agonists.<\/li>\n<li>[1:17:02] Beta-arrestin developments.<\/li>\n<li>[1:20:40] On Sasha Shulgin.<\/li>\n<li>[1:26:19] Strokes.<\/li>\n<li>[1:29:56] Cross-cultural considerations.<\/li>\n<li>[1:33:26] What do these therapies look like 10 years from now?<\/li>\n<li>[1:36:52] Gauging minimum effective dose.<\/li>\n<li>[1:42:58] The funding frustrations that almost made G\u00fcl give up science.<\/li>\n<li>[1:48:44] Taking risks.<\/li>\n<li>[1:52:59] What would G\u00fcl change about the way research is funded today?<\/li>\n<li>[1:55:57] Books most gifted.<\/li>\n<li>[1:59:10] Parting thoughts.<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">MORE DR. G\u00dcL D\u00d6LEN QUOTES FROM THE INTERVIEW<\/h3>\n<p><strong>\u201cI worked with my professors in philosophy in neuroscience primarily to come up with a curriculum that would span all of the different elements that I wanted to incorporate in trying to ask the question, \u2018What is the mind? What is consciousness? How do we know that from different perspectives?\u2019 And so the major was called Comparative Perspectives on the Mind, and it was a combination of neuroscience, philosophy, linguistics, art, and religion.\u201d<\/strong><\/p>\n<p>\u2014\u00a0Dr. G\u00fcl D\u00f6len<\/p>\n<p><strong>\u201cThe first day I saw the photograph of the molecule of LSD sitting right next to the molecule of serotonin and the similarities between them, I was like, \u2018This is it. This is how we\u2019re going to crack it. This is how we\u2019re going to get at those hard questions of neuroscience because here are chemicals that can alter our entire sense of reality, consciousness, perception, time, self, space, everything.\u2019 And I am not alone. I think most neuroscientists who have tried psychedelics would have exactly the same response.\u201d<\/strong><\/p>\n<p>\u2014\u00a0Dr. G\u00fcl D\u00f6len<\/p>\n<p><strong>\u201cPsychedelics have this property, which William James pointed out over 100 years ago, of creating this sense of what he called the noetic property, this feeling that \u2018Now that I\u2019ve had this experience, I know the really real. The true truth has been revealed to me and everything before this moment was just a facade or some lesser truth or some limited access to the truth. But now I really know.\u2019 For a scientist, that\u2019s pretty dangerous.\u201d<\/strong><\/p>\n<p>\u2014\u00a0Dr. G\u00fcl D\u00f6len<\/p>\n<p><strong>\u201cI think there was an intuition a few years ago that, well, indigenous people have been using psychedelics forever. We don\u2019t really need to understand their mechanisms, we don\u2019t really need to dig into how it is these things work because we know they\u2019re going to work because they\u2019ve got this long history behind them. But I think that if this ends up being true\u2014that this mechanistic explanation can really open up whole new avenues that people hadn\u2019t been thinking of before\u2014then I think that that\u2019s a testament to the importance of always keep an open mind, always look for more answers, more questions, and keep searching.\u201d<\/strong><\/p>\n<p>\u2014\u00a0Dr. G\u00fcl D\u00f6len<\/p>\n<p><strong>\u201cIf we\u2019re right and the critical period reopening explanation is this shift in the framework for how we understand these therapeutic effects, then in 10 years from now, the way that psychedelics are going to be used is going to be trying to identify that right context for the right disease. So while an inter-directed trip with a lot of psychotherapy makes a lot of sense for PTSD and addiction and depression, it\u2019s probably the wrong context for stroke.\u201d<\/strong><\/p>\n<p>\u2014\u00a0Dr. G\u00fcl D\u00f6len<\/p>\n<p><strong>\u201cI don\u2019t think I\u2019m unique for wanting to just see what happens when you give octopuses MDMA. In fact, I think the reason that everybody responded to that paper so well worldwide is because every single one of us has that curiosity, has that, \u2018I wonder what would happen?\u2019 It resonated with people, and I just think it mostly gets beaten out of us because of funding constraints.\u201d<\/strong><\/p>\n<p>\u2014\u00a0Dr. G\u00fcl D\u00f6len<\/p>\n<h3 class=\"wp-block-heading\">PEOPLE MENTIONED<\/h3>\n<p><h3 class=\"jp-relatedposts-headline\"><em>Related and Recommended<\/em><\/h3>\n<\/p>\n<p><em><a href=\"https:\/\/tim.blog\/podcast\" data-wpel-link=\"internal\"><strong>The Tim Ferriss Show<\/strong><\/a> <\/em><span>is one <\/span>of the most popular podcasts in the world with more than 900 million downloads. It has been selected for &#8220;Best of Apple Podcasts&#8221; three times, it is often the #1 interview podcast across all of Apple Podcasts, and it&#8217;s been ranked #1 out of 400,000+ podcasts on many occasions. To listen to any of the past episodes for free, check out <strong><a href=\"https:\/\/tim.blog\/podcast\" data-wpel-link=\"internal\">this page<\/a><\/strong>.<\/p>\n<\/p><\/div>\n<p><a href=\"https:\/\/hop.clickbank.net\/?affiliate=infohatch&amp;vendor=J1R2C\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-10614 aligncenter\" src=\"http:\/\/parmaks.com\/Resources\/wp-content\/uploads\/2025\/05\/profit-gen400px.png\" alt=\"Profit Gen\" width=\"400\" height=\"217\" srcset=\"https:\/\/parmaks.com\/Resources\/wp-content\/uploads\/2025\/05\/profit-gen400px.png 400w, https:\/\/parmaks.com\/Resources\/wp-content\/uploads\/2025\/05\/profit-gen400px-300x163.png 300w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/a><br \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Illustration via 99designs \u201cPsychedelics have this property, which William James pointed out over 100 years ago, of creating this sense of what he called the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2131,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-2130","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-growth"],"_links":{"self":[{"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/posts\/2130","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/comments?post=2130"}],"version-history":[{"count":0,"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/posts\/2130\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/media\/2131"}],"wp:attachment":[{"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/media?parent=2130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/categories?post=2130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/parmaks.com\/Resources\/wp-json\/wp\/v2\/tags?post=2130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}